July 2021

NAFLD as a metabolic disease, a review

A systematic literature review to identify recent epidemiological, biomarker, genetic and clinical evidence that expands our understanding of NAFLD as a metabolic disorder was performed by B. Cariou et al. (Inserm, CNRS, France). It appears that here is a growing body of evidence on the links between NAFLD/NASH pathogenesis and mechanisms of metabolic dysfunction…

Imaging biomarkers of NAFLD, NASH, and fibrosis

Globally, liver biopsy remains the reference standard for staging NAFLD severity. To diagnose NAFLD and quantify liver fat, MRI proton density fat fraction may be more informative than liver biopsy. In this review, V. Ajmera and R. Loomba (University of California, USA) critically examine the use…

July 29, 2021
Dr. Bozet
Definitions Articles, LATEST ARTICLE
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NAFLD as a metabolic disease, a review

A systematic literature review to identify recent epidemiological, biomarker, genetic and clinical evidence that expands our understanding of NAFLD.

July 29, 2021
Dr. Beard
Diagnosis Articles, LATEST ARTICLE
0 Comments

Imaging biomarkers of NAFLD, NASH, and fibrosis

In this review, V. Ajmera and R. Loomba critically examine the use of non-invasive imaging biomarkers to diagnose NAFLD, NASH, and fibrosis stage.

July 27, 2021
Prof. Schattenberg
Diagnosis Videos, HOME VIDEOS, Management Videos, VIDEOS
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NASH and quality of life

Prof Schattenberg, Germany, reviews how NASH impacts quality of life. He presents the mechanisms underlying metabolic comorbidities in NASH and discusses the relevant NASH phenotypes. A presentation of the tools that can be used to review health-related quality of life (HQRL) is particularly relevant for clinicians.

Pharmacotherapy in NAFLD/NASH

This review by SL Attia et al. (University of Kentucky College of Medicine, USA) summarises emerging pharmacotherapies for the treatment of adult and paediatric NAFLD. Investigated pharmacotherapies include lanifibranor (IVA337), an indole sulfonamide PPAR agonist that activates….

NAFLD: no liver biopsy in 2/3 patients of a real-world cohort

Much of the current data on NAFLD are derived from biopsy-based studies that may introduce ascertainment and selection bias. Selection of patients for liver biopsy has implications for clinical practice and the reported epidemiology of NAFLD. The aim of this study was to determine patient factors predictive….

July 26, 2021
Dr. Bozet
LATEST ARTICLE, Management Articles, PAN PPAR Articles
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Pharmacotherapy in NAFLD/NASH

This review by S. L. Attia et al. summarises emerging pharmacotherapies for the treatment of adult and paediatric NAFLD.

July 26, 2021
Dr. Beard
Diagnosis Articles, LATEST ARTICLE
0 Comments

NAFLD: no liver biopsy in 2/3 patients of a real-world cohort

The aim of this study was to determine patient factors predictive of histologic versus empiric clinical diagnosis of NAFLD in real-world practice.

Ethnicity and diversity in NAFLD

Globally, the rise in prevalence of obesity and metabolic syndrome as a whole has been linked to increased access to processed foods, such as refined sugars and saturated fats. Consequently, NAFLD is on the rise in both developed and developing nations.
This review by MAT Han et al…

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