Unhealthy lifestyles and diet contribute to the increasing prevalence of NAFLD/NASH
It is estimated that 25% of the global adult population is potentially affected by non-alcoholic fatty liver disease (NAFLD), with the highest prevalence in the Middle East and South America and the lowest in Africa. In the United States, approximately 25% of NAFLD patients have NASH, of which one-quarter have cirrhosis. Furthermore, the prevalence of NAFLD among children and adolescents is increasing, affecting approximately 3% to 10% of all children and over one-third of obese children in developed countries. The increasing prevalence of NAFLD is linked to a rise in other non-communicable diseases such as type 2 diabetes mellitus (T2DM), obesity and cardiovascular disease (CVD), which are primarily related to unhealthy lifestyles and diet. However, ageing and genetics might also play an important role, particularly in Native American and Hispanic populations.