Comorbidities in NAFLD/NASH and their complex interplay
NAFLD is often described as the hepatic manifestation of the metabolic syndrome. However, as pointed out by Bril and Cusi, NAFLD represents a complex disease process with both metabolic and liver complications, and it can be observed in patients with no clinical manifestations of the metabolic syndrome. Common comorbidities in NAFLD patients include obesity, insulin resistance and/or type 2 diabetes, dyslipidaemia, hypertriglyceridaemia, hypertension and cardiovascular disease.