PanNASH covers commented articles ans publications to acquire sufficient information, understanding, and skills to cope with NASH/NAFLD healthcare demands.
Although it is known that non-alcoholic steatohepatitis (NASH) increases the risk of end-stage liver diseases such as cirrhosis and hepatocellular carcinoma, no pharmacologic therapy has yet been approved to treat it.
Non-alcoholic fatty liver disease (NAFLD) is estimated to affect 25% of the world’s adult population. In 20% of these patients, NAFLD further develops into non-alcoholic steatohepatitis (NASH), which itself represents a leading cause of progression to liver cirrhosis and hepatocellular carcinoma.
Authors: Indira Chandran V, Wernberg CW, Lauridsen MM et al.
Published in Hepatology 2023
Although liver biopsy is the gold standard for the identification of non-alcoholic steatohepatitis (NASH), limits associated with its invasiveness justify research into non-invasive markers.
Non-alcoholic fatty liver disease (NAFLD) is the most prevalent chronic liver disease worldwide and a significant contributor to liver cirrhosis, transplantation, and hepatocellular carcinoma.
Published in The Lancet Gastroenterology and Hepatology 2022
Non-alcoholic fatty liver disease (NAFLD) is currently the fastest-growing indicator for liver transplantation worldwide. Its status as a growing health concern further parallels the global rise of obesity.
Data from the Global Burden of Disease study indicates that non-alcoholic fatty liver disease (NAFLD) is the most rapidly increasing global contributor to chronic liver disease (CLD)-associated complications, which include the onset of cirrhosis and hepatocellular carcinoma.
Published in Journal of Cachexia, Sarcopenia and Muscle 2023
It is known that traumatic muscle injury damages mitochondria, which may cause them to leak their contents into the cytoplasm and subsequently trigger calcium accumulation, cell death, endoplasmic reticulum stress, and the release of reactive oxygen species (ROS).
Walking speed (WS) is clinically recognized as a crucial vital sign. Associations between daily walking speed (DWS) and health outcomes have been underscored by a number of studies, which have further recognized it as an accurate predictor of dependency and mortality in elderly individuals. Despite this knowledge, very few studies have examined the link between DWS and frailty.
Authors: Schattenberg JM, Allen AM, Jarvis H et al.
Published in Communications Medicine 2022
The association between metabolic syndrome (MetS) and non-alcoholic fatty liver disease (NAFLD) has been well-characterised by recent literature. As such, patients with NAFLD are disproportionately affected by a range of comorbidities, which include obesity, dyslipidemia, type 2 diabetes mellitus (T2DM), and hypertension.
A non-invasive combined model termed FibroScan-aspartate aminotransferase (FAST) was recently proposed for the diagnosis of fibrotic non-alcoholic steatohepatitis (NASH). Conceptualised for patients with elevated non-alcoholic fatty liver disease (NAFLD) activity scores (≥4) and significant fibrosis
Cirrhosis is the end stage of a number of chronic liver diseases, including non-alcoholic steatohepatitis (NASH). Characterised by the scarring of liver tissue, cirrhosis leads to significant hepatic tissue distortion, which may subsequently cause portal hypertension, hepatic synthetic dysfunction, and hepatocellular carcinoma.
SUBSCRIBE TO OUR MONTHLY NEWSLETTER TO GET THE LATEST UPDATES
We use cookies on our website to give you the most relevant experience by remembering your preferences and repeat visits. By clicking “Accept All”, you consent to the use of ALL the cookies. However, you may visit "Cookie Settings" to provide a controlled consent.
This website uses cookies to improve your experience while you navigate through the website. Out of these, the cookies that are categorized as necessary are stored on your browser as they are essential for the working of basic functionalities of the website. We also use third-party cookies that help us analyze and understand how you use this website. These cookies will be stored in your browser only with your consent. You also have the option to opt-out of these cookies. But opting out of some of these cookies may affect your browsing experience.
Strictly necessary or essential cookies are absolutely necessary for the proper functioning of the website. This category only includes cookies that guarantee the basic functionality and security features of the website. Without these cookies, it would not be possible to access the services or the website and therefore this category cannot be disabled. These cookies do not store any personal information.
Cookie
Type
Duration
Description
AWSALB
First Party
7 days
This cookie is managed by Amazon Hosting AWSand is used for load balancing.
AWSALBTGCORS
First Party
7 days
This cookie is associated withAmazon Web Services Elastic Load Balancing functionality. It is used to honor sticky sessions and enable target group stickiness. When the load balancer first routes a request to a weighted target group, the cookie is generated and included in subsequent requests to the load balancer. It is used to route requests to the target group specified in the cookie. Specifically, the AWSALBTGCORS cookie is used with CORS (cross-origin resource sharing) requests that require the SameSite attribute to enable stickiness. It includes all the same information as the AWSALBTG cookie, plus the set SameSite attribute.
cli_user_preference
session
11 months
This cookie is set by GDPR Cookie Consent plugin. The purpose of this cookie is to store whether or not the user has given consent for cookie usage. It does not store any personal data.
cookielawinfo-checbox-analytics
persistent
11 months
This cookie is set GDPR Cookie Consent plugin . The purpose of this cookie is to check if the user has given consent to the use of cookies in the 'Analytics' category.
cookielawinfo-checbox-functional
persistent
11 months
This cookie is set by the GDPR Cookie Consent plugin . The purpose of this cookie is to check whether the user has given consent to the use of cookies in the category "Functional".
cookielawinfo-checkbox-necessary
persistent
11 months
This cookie is set by the GDPR Cookie Consent plugin . The purpose of this cookie is to check whether the user has given consent to the use of cookies in the category "Necessary".
cookielawinfo-checkbox-performance
persistent
11 months
This cookie is set by GDPR Cookie Consent plugin . The purpose of this cookie is to check if the user has given consent to the use of cookies in the "Performance" category.
CookieLawInfoConsent
session
11 months
This cookie is set by GDPR Cookie Consent plugin. It records the default button state of the corresponding category & the status of California Consumer Privacy Act (CCPA). It works only in coordination with the primary cookie, viewed_cookie_policy.
viewed_cookie_policy
persistant
11 months
The cookie is set by the GDPR Cookie Consent plugin and is used to store whether or not user has consented to the use of cookies. It does not store any personal data.
Functional cookies help to perform certain functionalities like sharing the content of the website on social media platforms, collect feedbacks, and other third-party features.
Cookie
Duration
Description
ppwp_wp_session
30 minutes
ppwp_wp_session is a cookie is native to PHP applications. The cookie is used to store and identify a users' unique session ID for the purpose of managing the user's session on the website. The cookie is a session cookie and is deleted when all browser windows are closed.
The services in this section allow the data controller to monitor and analyze traffic data and are used to track user behaviour.
The Google Analytics GA4 services used for our website allows us to record visitors and identify how we use the site. It is a statistical tool that allows us to improve our website taking into account the needs of visitors.
The data generated by these cookies concern:
website's use, as the pages visited;
your IP address to determine the connection city.
This data is immediately anonymized after localization
Cookie
Type
Duration
Description
_ga
session
2 years
This cookie is installed by Google Analytics GA4. The cookie is used to calculate the data of visitors, sessions, camapigns and keep track of the use of the site for the site analysis report. Cookies store information anonymously and assign a randomly generated number to identify unique visitors.
_ga_FG8ZN83T2T
session
2years
This cookie is installed by Google Analytics GA4. The cookie is used to distinguish users. Cookies store information anonymously and assign a randomly generated number to identify unique visitors.