H. pylori infection and NAFLD in China
The role of H. pylori infection in the development of NAFLD remains controversial. This retrospective study was conducted on 71,633 participants. .....
NASH Observatory
⏿ The PanNASH Initiative is an interactive web-based platform presenting global NASH statistics to inform NASH control and research.
Read MoreH. pylori infection and NAFLD in China
Accuracy of serum biomarkers versus liver biopsy
This first study on Croatian patients with NAFLD was conducted to evaluate the diagnostic performance of various biomarkers for steatosis, fibrosis, and inflammation in comparison to a liver biopsy.....
Psychological aspects of health behaviours in NAFLD non-alcoholic fatty liver disease
Prof. Maya Balakrishnan (USA) discusses the importance of the behavioural psychology in the field of non-alcoholic fatty liver disease, NAFLD.
Attenuation coefficient liver to spleen ratio and determination of hepatic steatosis
The aim of the study was to assess ultrasound attenuation coefficient in adult liver and spleen. The authors calculated attenuation coefficient liver to spleen ratio.....
Bile acids profile and transition from NAFLD into NASH
Metabolomic studies suggest plasma levels of bile acids are elevated amongst subjects with NAFLD compared to healthy controls. However, it remains unclear.....
Investigating hepatocellular inflammasome activation
Inflammasome activation followed by maturation has been observed in both preclinical models and NASH patients suggesting the crucial importance of inflammasome activation in NAFLD progression......
Pathophysiological roles of cell death in NASH
The conventional detection of necrosis in vivo is not currently available, whereas the detection method for apoptosis has been relatively well-established ....
Culture of mouse liver ductal organoids
3D organoid culture has become a powerful tool and model for various human diseases, including NASH. The hepatic progenitor cells can be induced to form hepatic organoids, .....
Purification and isolation of hepatic stellate cells
In an activated form, human hepatic stellate cells are the drivers of fibrosis following chronic liver injury. In NASH specifically, activated human hepatic stellate cells are drivers of induction and progression of fibrogenesis. .....
NASH Management in 2022: benefits of lifestyle recommendations, including nutrition and exercise
Prof. Stephen Harrison (USA) discusses state of the art management of non-alcoholic steatohepatitis (NASH) in 2022. He focuses on the benefits of lifestyle recommendations, including nutrition and exercise. He shows that weight loss is associated with NASH resolution and fibrosis regression over time following bariatric surgery in patients with severe obesity and NASH.
Getting to the Heart of NAFLD and NASH – The international CVD Perspective (part. 4)
This video presents a comprehensive review of non-alcoholic fatty liver disease (NAFLD) & non-alcoholic steatohepatitis (NASH), delivered by international experts with a multidisciplinary approach: Dr. Maarten Tushuizen, Prof. A.G (Onno) Holleboom, and Prof. Sven Francque, along with chair, Prof. Stefan Anker. They review the epidemiology of NAFLD / NASH, its increasing prevalence rates, and discuss current best practices to improve patient outcomes.
Study of hepatocytes: adenovirus for basic medical research
Deciphering the molecular mechanisms underlying the pathogenesis of NASH requires loss- or gain-of-function experimental approaches. Adenovirus is a fast, effective, and versatile tool that allows transient knockdown, .....