The circadian clock controls rhythms responsible for regulating bodily functions, e.g., appropriate eating times. When this clock becomes disrupted due to factors such as irregular daily eating patterns or weekly schedules, it instead promotes lipid dysregulation, oxidative stress, and inflammation.Read More
Authors: Cholankeril G, El-Serag H.
Published in Seminars in liver disease 2022
Nonalcoholic fatty liver disease (NAFLD) is characterised by the presence of hepatic steatosis without significant alcohol consumption or concomitant liver disease. Patients with NAFLD-related cirrhosis are at a high risk of developing liver complications, including hepatocellular carcinoma (HCC).Read More
Authors: Chen J, Dan L, Tu X et al.
Published in Hepatology International 2022
MAFLD and inflammatory bowel disease: a prospective cohort studyRead More
Coffee achieves its beneficial effects through modulation of insulin resistance in a NAFLD mouse model
Authors: Kakiyama G, Minowa K, Rodriguez-Agudo D et al.
Published in American Journal of Physiology, Gastrointestinal and Liver Physiology 2022
Coffee achieves its beneficial effects through modulation of insulin resistance in a NAFLD mouse modelRead More
Authors: Barrow F, Khan S, Fredrickson G, et al.
Published in Hepatology 2021
In this study, F. Barrow et al. (University of Minnesota Medical School, Minneapolis, USA) report that NASH livers accumulate B cells with elevated pro-inflammatory cytokine secretion .....Read More
Authors: antos-Laso A, Gutiérrez-Larrañaga M, Alonso-Peña M, et al.
Published in Biomedicines 2021
In this review, A. Santos-Laso et al. (Marqués de Valdecilla University Hospital, Valdecilla Biomedical Research Institute, Santander, Spain) summarise the key aspects of NAFLD .....Read More
Authors: Geier A, Tiniakos D, Denk H, et al.
Published in Gut 2021
Although the term 'fatty liver hepatitis' first appeared in 1962, it was in 1980 that the term 'non-alcoholic steatohepatitis' (NASH) was coined and the histopathological.....Read More
Authors: Huby T, Gautier EL.
Published in Nat Rev Immunol 2022
In this review, T. Huby and E. L. Gautier (Sorbonne Université, Hôpital de la Pitié-Salpêtrière, Paris, France) discuss “current concepts related to the.....
Authors: Abuja PM, Zatloukal K, Denk H.
Published in Int J Mol Sci 2021
In this article, P. M. Abuja et al. (Medical University of Graz, Austria) propose that steatohepatitis develops in four phases with transitions, priming triggering, adaptation....Read More
Authors: Younossi ZM, Henry L.
Published in Endocr Pract 2022
In this article, Z. M. Younossi et al. (Inova Health System, Falls Church, VA, USA) aimed to review the current literature on NAFLD and NASH as it impacts children and adults....Read More
Authors: Toobian D, Ghosh P, Katkar GD.
Published in Front Immunol 2021
In this review, D. Toobian et al. (University of California San Diego, CA, USA) underline emerging evidence of the potential roles of the PPAR subtypes in macrophage.....
Authors: Kanwal F, Shubrook JH, Adams LA, et al.
Published in Gastroenterology 2021
The American Gastroenterological Association assembled a multidisciplinary panel of experts to develop a Clinical Care Pathway providing explicit guidance on the.....Read More