On International NASH Day 2023, PanNASH amplifies the importance of NASH awareness, education, and action. Learn about the complex multisystem nature of NASH, the potential of PPAR agonists in NASH management, and the role of healthcare professionals in delivering effective, patient-centered care. Discover how PanNASH resources are empowering the medical community and join us in taking action against NASH.Read MoreInternational NASH Day 2023: Empowering Healthcare Professionals
PanNASH speaker; Dr. Stephen Harrison takes part in the Nordic NASH symposium which aims to discuss management and diagnosis strategies of improving outcomes for patients with non-alcoholic steatohepatitis (NASH)Read MoreNordic NASH Symposium
The circadian clock controls rhythms responsible for regulating bodily functions, e.g., appropriate eating times. When this clock becomes disrupted due to factors such as irregular daily eating patterns or weekly schedules, it instead promotes lipid dysregulation, oxidative stress, and inflammation.Read MoreThe role of circadian clocks in the pathogenesis of NAFLD
Authors: Cholankeril G, El-Serag H.
Published in Seminars in liver disease 2022
Nonalcoholic fatty liver disease (NAFLD) is characterised by the presence of hepatic steatosis without significant alcohol consumption or concomitant liver disease. Patients with NAFLD-related cirrhosis are at a high risk of developing liver complications, including hepatocellular carcinoma (HCC).Read MoreHepatocellular carcinoma surveillance in NAFLD patients
Authors: Chen J, Dan L, Tu X et al.
Published in Hepatology International 2022
MAFLD and inflammatory bowel disease: a prospective cohort studyRead MoreMAFLD and inflammatory bowel disease: a prospective cohort study
Coffee achieves its beneficial effects through modulation of insulin resistance in a NAFLD mouse model
Authors: Kakiyama G, Minowa K, Rodriguez-Agudo D et al.
Published in American Journal of Physiology, Gastrointestinal and Liver Physiology 2022
Coffee achieves its beneficial effects through modulation of insulin resistance in a NAFLD mouse modelRead MoreCoffee achieves its beneficial effects through modulation of insulin resistance in a NAFLD mouse model
Authors: Barrow F, Khan S, Fredrickson G, et al.
Published in Hepatology 2021
In this study, F. Barrow et al. (University of Minnesota Medical School, Minneapolis, USA) report that NASH livers accumulate B cells with elevated pro-inflammatory cytokine secretion .....Read MoreB cells aggravate NASH: an innate and adaptive signalling
Authors: antos-Laso A, Gutiérrez-Larrañaga M, Alonso-Peña M, et al.
Published in Biomedicines 2021
In this review, A. Santos-Laso et al. (Marqués de Valdecilla University Hospital, Valdecilla Biomedical Research Institute, Santander, Spain) summarise the key aspects of NAFLD .....Read MoreNAFLD: from drivers to targets
Authors: Geier A, Tiniakos D, Denk H, et al.
Published in Gut 2021
Although the term 'fatty liver hepatitis' first appeared in 1962, it was in 1980 that the term 'non-alcoholic steatohepatitis' (NASH) was coined and the histopathological.....Read MoreNASH: an Overview Through 200 Years of Clinical Research
Authors: Huby T, Gautier EL.
Published in Nat Rev Immunol 2022
Read MoreImmune cell-mediated features of NASH
In this review, T. Huby and E. L. Gautier (Sorbonne Université, Hôpital de la Pitié-Salpêtrière, Paris, France) discuss “current concepts related to the.....
Authors: Abuja PM, Zatloukal K, Denk H.
Published in Int J Mol Sci 2021
In this article, P. M. Abuja et al. (Medical University of Graz, Austria) propose that steatohepatitis develops in four phases with transitions, priming triggering, adaptation....Read MoreSteatohepatitis: hypothesis for a pathomechanism
Authors: Younossi ZM, Henry L.
Published in Endocr Pract 2022
In this article, Z. M. Younossi et al. (Inova Health System, Falls Church, VA, USA) aimed to review the current literature on NAFLD and NASH as it impacts children and adults....Read MoreFatty liver through the ages: Nonalcoholic steatohepatitis