Investigating hepatocellular inflammasome activation

Inflammasome activation followed by maturation has been observed in both preclinical models and NASH patients suggesting the crucial importance of inflammasome activation in NAFLD progression......
PUBLISHED IN: Methods Mol Biol 2022

Commentary

Inflammasome activation followed by maturation has been observed in both preclinical models and NASH patients suggesting the crucial importance of inflammasome activation in NAFLD progression.

In this article, D. Das et al. (CSIR-Indian Institute of Chemical Biology, Kolkata, India) describe an ex vivo method for investigating the role of inflammasome activation in macrophages and its impact on hepatocytes. It provides a comprehensive protocol for investigating hepatocellular inflammasome activation.

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Dr. G. Bozet, MD

Dr. G. Bozet, MD

Articles: 173

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