Authors: Purssell H, Whorwell PJ, Athwal VS, et al.
Published in World J Hepatol 2021
Recently, there has been interest in the apparent co-incidence of NAFLD in patients with IBS mainly driven by improved understanding of their shared risk factors and pathophysiology H. Purssell et al. (Manchester University NHS Foundation Trust, UK)......
J. Romano et al. (Medical University of South Carolina, Charleston, USA) evaluated whether these non-invasive markers and/or any other clinical parameters may be used to identify patients with liver cirrhosis who are likely to have large....
Liver homeostasis is strongly influenced by the circadian clock. Disruption of the clock has been heavily implicated in the pathogenesis of NAFLD and NASH. There has been little consideration of the application of chronopharmacology in NASH, a strategy whereby.....
Authors: Sugiyama H, Kobayashi Y, Sumida Y, et al.
Published in J Clin Biochem Nutr 2022
The aim of this study was to investigate whether a nutritional intervention motivating increased vegetable consumption would be an effective treatment and diet therapy for patients with non-alcoholic fatty liver disease. During the 6-month intervention .....
Authors: Thiagarajan S, Shrinuvasan S, Arun Babu T.
Published in Indian J Gastroenterol 2022
NAFLD is increasingly recognised in obese and overweight children. In this cross-sectional study, S. Thiagarajan et al. (Indira Gandhi Medical College and Research Institute, India) aimed to assess the prevalence of NAFLD in this population and to identify the associated....
Oncostatin M is a pleiotropic cytokine of the interleukin (IL)-6 family that contributes to the progression of chronic liver disease. G. Di Maira et al. (University of Firenze, Italy) aimed to investigate the role of oncostatin M in the development and progression of hepatocellular.....
This slides set presents a detailed review of vascular alterations in non-alcoholic steatohepatitis (NASH) and NASH cirrhosis delivered by Professor Francque, MD, PhD. He highlights that non-fibrotic non-alcoholic fatty liver disease (NAFLD) is accompanied by a significant rise in portal pressure. Professor Francque, also explains the effects of intrahepatic vascular resistance increase in NAFLD. To the clinicians, he provides various patient studies, statistics and clinical data on the subject.
Authors: Pais R, Aron-Wisnewsky J, Bedossa P, et al.
Published in Hepatology 2022
R. Pais et al. (Hôpital Pitié-Salpêtrière, Paris, France) describe the histological outcome in patients with advanced NASH and its relationship with weight loss and metabolic improvement after bariatric surgery. For the authors, “while bariatric surgery successfully...
This review by C. H. Lee et al. (University of Hong Kong, Hong Kong) aims to provide a summary of the latest evidence that support NAFLD as an emerging diabetic complication of increasing importance, and to present the current recommendations...
This multidisciplinary discussion on the diabetologist's and hepatologist's perspectives of non-alcoholic fatty liver disease (NAFLD) / non-alcoholic steatohepatitis (NASH), involves international experts, Dr. Maarten Tushuizen, Prof. A.G (Onno) Holleboom and Prof. Christophe Moreno, together with the chair, Professor Manuel Castor Cabezas. The review addresses NAFLD as a multisystem disease, its epidemiology globally and the significance of developing multidisciplinary care paths.
MicroRNA levels in blood may change in liver disease including NAFLD. K. Johnson et al. (Newcastle University, UK) carried out microRNA sequencing in a group of 183 patients with NAFLD. One particular microRNA miR-193a-5p consistently increased...
MAFLD might be considered as a multisystem disease that affects not only the liver but involves wider implications, relating to several organs and systems, the brain included.The present study by S. Nucera et al. (University Magna Graecia of Catanzaro, Italy) ...
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