NASH-related fibrosis: MEFIB has higher diagnostic accuracy than FAST
H. pylori infection and NAFLD in China
The role of H. pylori infection in the development of NAFLD remains controversial. This retrospective study was conducted on 71,633 participants. .....
Bile acids profile and transition from NAFLD into NASH
Metabolomic studies suggest plasma levels of bile acids are elevated amongst subjects with NAFLD compared to healthy controls. However, it remains unclear.....
Pathophysiological roles of cell death in NASH
The conventional detection of necrosis in vivo is not currently available, whereas the detection method for apoptosis has been relatively well-established ....
Culture of mouse liver ductal organoids
3D organoid culture has become a powerful tool and model for various human diseases, including NASH. The hepatic progenitor cells can be induced to form hepatic organoids, .....
Study of hepatocytes: adenovirus for basic medical research
Deciphering the molecular mechanisms underlying the pathogenesis of NASH requires loss- or gain-of-function experimental approaches. Adenovirus is a fast, effective, and versatile tool that allows transient knockdown, .....
NASH: Bile acid profiling
Bile acids synthesis and metabolism have been impaired in NASH patients because of liver injury, inflammation or obstruction of bile ducts. Changes in bile acids composition might contribute to NASH .....
NAFLD signature in adipose tissue
Development and severity of NAFLD have been linked to obesity and white adipose tissue dysfunction plays a key role in this relation. Ó. Osorio-Conles et al. ....
Heart rate variability and risk of NAFLD
I. Y. CHoi et al. (Total Healthcare Centre, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, South Korea) investigated the association .....
Colonic Diverticulosis and NAFLD
This retrospective study aimed to evaluate a possible connection between NAFLD, colonic diverticulosis, and metabolic syndrome.For the authors,......
Non-invasive risk stratification in NAFLD/NASH patients for screening esophagogastroduodenoscopy
J. Romano et al. (Medical University of South Carolina, Charleston, USA) evaluated whether these non-invasive markers and/or any other clinical parameters may be used to identify patients with liver cirrhosis who are likely to have large....