Delve into the latest in medical education resources for NASH. Explore new studies, teaching methodologies, and advancements shaping NASH education for healthcare professionals.
Published in Journal of Hepatology (February 2023)
Mitochondria play a pivotal role in numerous features of hepatic function, driving processes such as substrate metabolism, energy production through cellular signalling, and biotransformation of xenobiotics.
In patients with non-alcoholic steatohepatitis (NASH), the risk of liver-related mortality and decompensation is known to increase proportionally with fibrosis stage. Non-invasive tools, including liver stiffness by vibration-controlled transient elastography (LS-VCTE), have been shown to accurately predict fibrosis stage in NASH patients.
Non-alcoholic fatty liver disease (NAFLD) is a major contributor to liver-related illnesses and fatalities worldwide. Its clearly established two-way connection with obesity, a significant public health issue showing increasing prevalence rates globally and regionally, necessitates comprehensive education focused on NAFLD and the implementation of worldwide policies to address it effectively.
Authors: Kalavalapalli S, Leiva EG, Lomonaco R et al.
Published in Journal of Clinical Endocrinology and Metabolism (April 2023)
Understanding the drivers of non-alcoholic fatty liver disease (NAFLD) is crucial to developing pharmacotherapies that effectively target it. Insulin resistance (IR), whose onset precipitates type 2 diabetes (T2D), is known to play a crucial role in the development of hepatic steatosis.
The multinational liver societies introduce a non-stigmatizing and affirming nomenclature for "Fatty" liver diseases, striving for a global consensus to advance research, funding, and patient care.
Disease awareness, patient stratification, diagnosis, and access to care are all helped or hindered by a pathology’s nomenclature. Indeed, the language used to name and identify a disease has the power to create or intensify social stigma, marginalise subsets of a patient population, and perpetuate health inequalities.
Authors: Stols-Gonçalves D, Mak AL, Madsen MS et al.
Published in Gut Microbes (June 2023)
Patients with non-alcoholic fatty liver disease (NAFLD) exhibit alterations in their gut microbiota composition. Indeed, both nuclear and mitochondrial DNA methylation have been linked to the development of NAFLD and metabolic diseases, including obesity and type 2 diabetes mellitus.
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