Epidemiology Articles

Gain free access to the latest articles on the NASH and NAFLD epidemic by a global expert community. ⌨

Global research on fatty liver disease: a review

Authors: Lazarus JV, Mark HE, Allen AM, et al.
Published in J Hepatol (September 2023)
In this study, a large, global, multidisciplinary panel discussed priorities within the field of fatty liver disease, including its burden, policies surrounding the issue and treatment options.
Read MoreGlobal research on fatty liver disease: a review

Managing Hepatocellular Carcinoma in NAFLD: a review

Authors: Cadar R, Lupascu Ursulescu C, Vasilescu AM, et al
Published in Life (Basel) (September 2023)
Currently, there are rising levels of non-alcoholic fatty liver disease (NAFLD). With this, comes a concurrent increase in hepatocellular carcinoma (HCC) cases.
Read MoreManaging Hepatocellular Carcinoma in NAFLD: a review

The new paradigm of cardiometabolic syndrome: a review

Authors: Khan AR, Salama AH, Aleem Z, et al.
Published in Cureus (September 2023)
Cardiometabolic syndrome (CMS) involves a complex interplay of many issues, involving obesity, metabolic dysregulation, cardiovascular disease, insulin resistance and more. This condition extends to clinical implications including non-alcoholic fatty liver disease (NAFLD) as well as cancer and sleep apnoea.
Read MoreThe new paradigm of cardiometabolic syndrome: a review

Discerning sex-related differences in NAFLD patients via metabolic profiling

Authors: Fotakis C, Kalafi IP, Amanitidou AI et al.
Published in Frontiers in Endocrinology (October 2023)
Research into personalised medicine for non-alcoholic fatty liver disease (NAFLD) underscores the importance of acknowledging NAFLD patients’ unique clinical phenotypes when developing targeted pharmacotherapies.
Read MoreDiscerning sex-related differences in NAFLD patients via metabolic profiling

Research Priorities in NAFLD: Ensuring Personalised and Multidisciplinary Patient Care

Authors: Iruzubieta P, Bataller R, Arias-Loste MT et al.
Published in Clinics in Liver Disease (May 2023)
Both non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH), NAFLD’s inflammatory and progressive subtype, are the histologic manifestations of a heterogeneous disease intricately linked with metabolic disorders.
Read MoreResearch Priorities in NAFLD: Ensuring Personalised and Multidisciplinary Patient Care

The Long Road to NASH Therapeutics: Uncovering Valuable Insights

Authors: Tilg H, Byrne CD and Targher G
Published in The Lancet Gastroenterology and Hepatology (October 2023)
Recent research indicates that 30% of adults worldwide, 90% of those with obesity, and 70% with type 2 diabetes are affected by non-alcoholic fatty liver disease (NAFLD).
Read MoreThe Long Road to NASH Therapeutics: Uncovering Valuable Insights

Liver Stiffness and All-Cause Mortality in NAFLD Patients: Is There an Independent Link?

Authors: Ciardullo S, Muraca E, Zerbini F et al.
Published in Liver International (September 2023)
Liver-related events contribute to a small proportion of mortality within the collective cohort of patients with non-alcoholic fatty liver disease (NAFLD).
Read MoreLiver Stiffness and All-Cause Mortality in NAFLD Patients: Is There an Independent Link?

NAFLD and Pancreatic Steatosis: A Bidirectional Relationship?

Authors: Wongtrakul W, Untaaveesup S, Pausawadi N et al.
Published in European Journal of Gastroenterology & Hepatology (October 2023)
Recent research supports the existence of a potential link between non-alcoholic fatty liver disease (NAFLD) and fatty pancreas.
Read MoreNAFLD and Pancreatic Steatosis: A Bidirectional Relationship?

Examining the Role of Abnormal Mitochondrial in Fatty Liver Diseases

Authors: Fromenty B, Roden M
Published in Journal of Hepatology (February 2023)
Mitochondria play a pivotal role in numerous features of hepatic function, driving processes such as substrate metabolism, energy production through cellular signalling, and biotransformation of xenobiotics.
Read MoreExamining the Role of Abnormal Mitochondrial in Fatty Liver Diseases

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