Search Results for Fibrosis

V. Houttu et al. (Department of Experimental Vascular Medicine, University of Amsterdam, Amsterdam, The Netherlands) review the current literature on exercise and the gut microbiome in NAFLD. The human gut microbiome has been found to influence...

The topic of liver biopsy in clinical studies, such as for treatments for NASH, is highly important. Despite limitations, liver biopsy remains the gold standard for the study of liver disease. It is important for the exclusion of alternative diseases and co-morbidities such as autoimmune hepatitis or primary biliary cholangitis...

Obstructive sleep apnea (OSA) is associated with the development and evolution of NAFLD, independent of obesity or other shared risk factors. The OSA–NAFLD association is related to the degree of nocturnal hypoxaemia in OSA. Animal models have largely focused on intermittent hypoxia, a key manifestation of OSA...

Two new position papers convincingly propose that non-alcoholic fatty liver disease needs a new name — metabolic associated fatty liver disease (MAFLD). A new name for this disease affecting nearly one billion people globally is overdue, as knowledge gained from the past decades has definitely demonstrated that MAFLD is a purely metabolic disorder...

Low awareness can delay healthcare screening and prevention of NAFLD and its related complications. Therefore, low awareness of NAFLD among the general population is a matter of great concern. This is also important for resource allocation, and the creation and implementation of awareness programs....

NAFLD is closely related to features of the metabolic syndrome including type 2 diabetes. P. Nasr et al. (Linköping University, Sweden) investigated the importance of the amount of liver fat on mortality and the risk of developing type 2 diabetes. In 129 patients with biopsy proven NAFLD prospectively...

Non-Alcoholic Fatty Liver Disease (NAFLD) represents an increasing cause of liver disease worldwide. However, notably, the primary cause of morbidity and mortality in patients with NAFLD is cardiovascular disease (CVD), with fibrosis stage being the strongest disease-specific predictor. Within the next few years, NAFLD will contribute considerably to the overall...