Obese NAFLD children and adolescents: high BMI predicts liver fibrosis

H. Moran-Lev et al. (Dana Dwek Children’s Hospital, Tel Aviv University, Israel) aimed to investigate the predictors for liver fibrosis and the effects of short-term nutritional intervention on steatosis and fibrosis among obese adolescents with NAFLD...
PUBLISHED IN: BMC Pediatr 2021

Commentary

H. Moran-Lev et al. (Dana Dwek Children’s Hospital, Tel Aviv University, Israel) aimed to investigate the predictors for liver fibrosis and the effects of short-term nutritional intervention on steatosis and fibrosis among obese adolescents with NAFLD.

The authors prospectively recruited all children and adolescents with a BMI >95 percentile for age who were admitted to the Obesity Clinic at Dana-Dwek Children’s Hospital of the Tel Aviv Medical Center between December 1, 2018, and December 1, 2019.

The results of the present study indicate that higher BMI levels and moderate/severe liver steatosis are predictors for severe liver fibrosis in children and adolescents. Three months of nutritional intervention based on a low carbohydrate diet improved hepatic steatosis and fibrosis in a paediatric population with NAFLD.

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Dr. D. Beard

DR. D. BEARD is specialist of Nash Pathology

Articles: 191

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