Commentary
An association between NAFLD and brain aging has been suggested. Therefore, C. Labenz et al. aimed to investigate the hypothesis if NAFLD is an independent risk factor for emerging dementia.
In a population-based cohort study, a total of 22,317 elderly patients with NAFLD were matched to 22,317 patients without NAFLD. Within 10 years of the index date, 16.0% of patients with NAFLD and 15.6% of the patients without NAFLD were diagnosed with dementia. On Cox regression analysis, there is no association between NAFLD and the incidence of all-cause dementia, vascular dementia, or the new prescription of antidementive therapy.
