Epidemiology Articles

P. Golabi et al. assessed the burden of liver complications (cirrhosis and liver cancer) related to NAFLD between 2009-2019 in Asia and MENA (Middle East and Northern Africa) regions, using Global Burden of Disease data to assess incidence, mortality, and disability-adjusted-life-years (DALYs)...

X. Zhang et al. (Fudan University, Shanghai, China) collected, from the Global Burden of Disease database, annual cases, and prevalence of NAFLD/NASH from 1990 to 2017, by sex, region and country. This study shows that both the prevalence and number of cases of NAFLD/NASH have...

M. G. Swain et al. (University of Calgary, Canada) used a Markov model to forecast the burden of disease of NAFLD and NASH among Canadians with NAFLD from 2019 to 2030. The model projected that the number of NAFLD cases would increase by 20% between 2019 and 2030. Increasing rates of obesity ...

The burden of NAFLD/NASH manifests in increasing levels of advanced liver disease and primary liver cancer in Australia. L. A. Adams et al. (The University of Western Australia, Perth, Australia) used a Markov model to forecast NAFLD burden in Australia through 2030. Prevalent NAFLD cases were projected to increase 25% from the current...

For J. Zhou et al. (Wuhan University, China), NAFLD has become the most prevalent liver disorder in China but has not received sufficient attention. NAFLD-related advanced liver disease and its mortality along with its overall disease burden are expected to increase substantially. In their meta-analysis, the authors summarise eight...

The aim of this study by R. Loomba et al. (NAFLD Research Center, University of California, San Diego, USA) was to evaluate the impact of disease severity, demographics and comorbidities on risk of mortality and time to progression in a large, real-world cohort of diagnosed NAFLD patients...

S. A. Harrison et al. (Radcliffe Department of Medicine, University of Oxford, UK) prospectively assessed the prevalence and severity of NAFLD/NASH in a cohort of asymptomatic middle-aged Americans attending a colonoscopy class at a gastroenterology clinic. Screening for NAFLD was performed using magnetic resonance...

This study comprehensively investigated temporal trends in NAFLD prevalence at the global, regional, and national levels. The study included 21 regions and 195 countries or territories. The authors assessed secular trends in NAFLD risk factors, according...

This review by A. Majumdar (Australian National Liver Transplant Unit, Royal Prince Alfred Hospital, Sydney, and University of Sydney, Australia) and E. Tsochatzis (UCL Institute for Liver and Digestive Health, Royal Free Hospital and UCL, London, and Sheila Sherlock Liver Centre, Royal Free Hospital, London, UK) outlines the current epidemiology, natural history...

The study by KWM Abeysekera et al. (Population Health Sciences, Bristol Medical School, University of Bristol, and University Hospitals Bristol NHS Foundation Trust, Bristol, UK) is the first to determine the prevalence of NAFLD in young adults with use of transient electrography, in an age group in which NAFLD burden is poorly characterized...

Data on NALFD epidemiology in the Asia-Pacific region indicate a rapid increase in the disease’s burden over the past three decades, which is supported by a systematic review and meta-analysis that assessed the prevalence, incidence, and outcomes of NAFLD in Asia. The analysis estimated that the overall prevalence of NAFLD...