Commentary
High levels of physical activity and cardiorespiratory fitness may protect against NAFLD. C. J. Kerr et al. (University of Essex, UK) investigated whether different physical activity intensities, and cardiorespiratory fitness, were independent predictors of non-alcoholic fatty liver disease.
The authors found the lowest prevalence of NAFLD in adults achieving >60 min per week of vigorous physical activity. A stronger dose-response relationship existed between cardiorespiratory fitness, estimated by incremental treadmill test, and non-alcoholic fatty liver disease.
Improving cardiorespiratory fitness as a potential therapeutic target for treatment and prevention of non-alcoholic fatty liver disease warrants further investigation.
