What are the current definitions ? Prof Abdelmalek, USA

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So NAFLD (non-alcoholic fatty liver disease) is a spectrum of disease that spans from simple steatosis or simple fatty liver to an indeterminate stage called NASH (non-alcoholic steatohepatitis) which is characterized by the inflammation, ballooned hepatocytes and even early fibrosis. Fibrosis can span from  mild to advanced or cirrhosis so the spectrum of NAFLD can span anything from simple steatosis all the way to cirrhosis, with patients that have non-alcoholic steatohepatitis being at the increased risk for developing advanced liver disease.

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Prof. M. F. Abdelmalek

Prof. M. F. Abdelmalek

Manal F. Abdelmalek, MD, MPH is Director of Hepatology and institutional lead for investigator-initiated and industry-sponsored multicenter clinical studies, Mayo Clinic, USA. Until recently, she was tenured Professor of Medicine in the Division of Gastroenterology and Hepatology at...

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