Imaging biomarkers in NAFLD: Could they avoid liver biopsy
There is a need for new biomarkers that allow the detection and quantification of liver diseases supported on the measurement of fat, iron, fibrosis, inflammation. Dr Romero-Gomez presents a state-of-the-art video on imaging biomarkers with the pros and cons for each technology. For daily practice, he also suggests a diagnosis algorithm
The diagnosis of NASH is critically important for clinical trials and clinical practice. Today, the gold standard to diagnose NASH is a liver biopsy, as it’s the most complete diagnostic solution allowing clinicians to study key characteristics of the disease. But it has limitations. Liver biopsies require significant expertise both to perform but also to interpret the results. Biomarkers could play an important role and imaging biomarkers (transient elastography and shear-wave) plus MRI techniques allow assessment of liver damage in NAFLD with high diagnostic accuracy.
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Inflammation in NASH and the transition to HCC: an update on scientific breakthroughs by Dr Peiseler and Prof Tacke, Germany
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From number-one liver disease to multi-system disease: NASH, a major unmet clinical need