Commented Articles

In this study, S. Ciardullo et al. (Università degli Studi di Milano Bicocca, Italy) present a population-based cross-sectional study including 2734 US adults using data from the 2017-2018 cycle of the National Health and Nutrition Examination Survey The authors show that “patients with NAFLD have....

This article describes the complex interactions occurring between diet, the gut microbiome, and bile acids in the aetiology of fatty liver disease. Emerging new molecular technologies may provide guidance in unraveling the complex physiological pathways driving fatty liver disease and better....

In this review, Yumi Ando and Janice H. Jou (Portland, OR, USA) summarise updated guidelines and guidance recommendations for the management of adult NAFLD. Interestingly, the authors highlight key difference between US, Asian, and European recommendations; and provide key updates....

Although liver fat is associated with cardiovascular risk factors, the association between hepatic fibrosis and cardiovascular risk factors is less clear. M. T. Long et al. (Boston University School of Medicine, USA) performed vibration-controlled transient elastography, assessing controlled attenuation parameter...

NAFLD is an increasingly prevalent and potentially severe liver disease, emphasising the need for implementation of widely supported care paths for patients at risk for advanced stages of NAFLD. In this review article by A. M. van Dijk et al. (Amsterdam University Medical Centre, The Netherlands), after...

This brief review by Kathleen E. Corey et al. (Liver Center, Massachusetts General Hospital, Boston, MA, USA) provides a pragmatic guide of cardiovascular disease in NAFLD, with a focus on coronary heart disease...

These Korean guidelines, organised in accordance with proposals by the approval of the Korean Association for the Study of the Liver (KASL) Board of Executives, provide clinical information and direction to healthcare providers involved in the diagnosis and treatment of NAFLD patients. ...

Using a meta-analytic approach, J. Park et al. (Santa Clara Valley Medical Center, San Jose, CA, USA) aimed to describe NAFLD incidence and prevalence, NAFLD fibrosis prevalence, and incidence of non-liver comorbidities. In this study, the overall prevalence of NAFLD was 31.46% with an incidence rate of 42.8 per 1,000 person-years...

The majority of NAFLD patients die of cardiovascular disease. For this reason, management of this condition requires a multidisciplinary team. However, important misconceptions remain among primary care providers. NAFLD should be understood as part of a systemic disease characterized ...

Several studies provide evidence for an association between MAFLD and atherosclerosis and cardio-metabolic disorders, including cardiovascular diseases such as coronary heart disease and stroke. Therefore, the combination of MAFLD/NASH is associated with vascular risk and CVD progression, but the underlying mechanisms...

Exercise could mediate its beneficial effects directly on the liver and indirectly via extrahepatic pathways, forming a dose-response relationship with NAFLD in terms of prevalence and disease severity...

The authors evaluated the impact of NAFLD on the risk of low muscle mass and low muscle strength in a nationwide multicentre study in a total of 1595 community-dwelling people aged 70-84 years were followed for 2 years in the Korean Frailty and Aging Cohort Study...