Evidence linking obesity with MAFLD, NASH, and CVD

Several studies provide evidence for an association between MAFLD and atherosclerosis and cardio-metabolic disorders, including cardiovascular diseases such as coronary heart disease and stroke. Therefore, the combination of MAFLD/NASH is associated with vascular risk and CVD progression, but the underlying mechanisms...
PUBLISHED IN: Int J Mol Sci 2021

Commentary

Several studies provide evidence for an association between MAFLD and atherosclerosis and cardio-metabolic disorders, including cardiovascular diseases such as coronary heart disease and stroke. Therefore, the combination of MAFLD/NASH is associated with vascular risk and CVD progression, but the underlying mechanisms linking MAFLD/NASH and CVD are still under investigation.

In this review, J. Gutiérrez-Cuevas et al. (University of Guadalajara, Jalisco, Mexico) summarise the evidence linking obesity with MAFLD, NASH, and CVD, and discuss the association of MAFLD and NASH with the development and progression of CVD.

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Dr. G. Bozet, MD

Dr. G. Bozet, MD

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