Hepatic fibrosis and CV risk factors: the Framingham Heart Study

Commentary

Although liver fat is associated with cardiovascular risk factors, the association between hepatic fibrosis and cardiovascular risk factors is less clear. M. T. Long et al. (Boston University School of Medicine, USA) performed vibration-controlled transient elastography, assessing controlled attenuation parameter and liver stiffness measurement in 3,276 Framingham Heart Study adult participants presenting for a routine study visit.

After a multivariable-adjusted logistic regression, vibration-controlled transient elastography-defined hepatic fibrosis appeared associated with multiple cardiovascular risk factors, including obesity, metabolic syndrome, diabetes, hypertension, and HDL cholesterol.