NASH: an Overview Through 200 Years of Clinical Research

Commentary

Although the term ‘fatty liver hepatitis’ first appeared in 1962, it was in 1980 that the term ‘non-alcoholic steatohepatitis’ (NASH) was coined and the histopathological hallmarks that are still valid today were defined.
A. Geier et al. (Division of Hepatology, Department of Medicine II, University Hospital Würzburg, Bayern, Germany) provide “an overview through almost two hundred years of clinical research from the beginnings as a nebulous disease entity of unknown origin in the 19th century to the most frequent and vigorously investigated liver disease today.”