Commentary
The burden of NAFLD/NASH manifests in increasing levels of advanced liver disease and primary liver cancer in Australia. L. A. Adams et al. (The University of Western Australia, Perth, Australia) used a Markov model to forecast NAFLD burden in Australia through 2030.
Prevalent NAFLD cases were projected to increase 25% from the current burden. Incident cases of advanced liver disease are projected to increase up to 85% by 2030, and incident NAFLD liver deaths are estimated to increase 85%.
It appears that restraining growth of the obese and diabetic populations, along with potential therapeutic options, will be essential for mitigating disease burden.
Hepatic inflammatory responses in liver fibrosis