Commented Articles

The association of free testosterone with NASH was determined in pre-menopausal women with biopsy-confirmed NAFLD. Interaction testing was performed for age and free testosterone given decline in testosterone with age, and association of aging with...

Several strategies are available for detecting cirrhosis in patients with NAFLD, but their cost effectiveness is not clear. E. Vilar-Gomez et al. (Department of Medicine, Indiana University School of Medicine, Indianapolis, Indiana, USA) developed a decision model to...

The gut microbiome plays a role in metabolism and maintaining gut barrier integrity, and fecal microbiota transplantation can be used to alter the gut microbiome. The authors hypothesized that a fecal microbiota transplantation from a thin and healthy donor given to patients with NAFLD...

NAFLD and hepatocellular carcinoma are strongly associated with obesity, insulin resistance and the metabolic syndrome and directly attributed to changes in lifestyle, especially dietary patterns and sedentary behaviour. Western diet and cholesterol contained in the diet exacerbate hepatic accumulation of free cholesterol, resulting in the toxic effects on the liver...

Liver stiffness, as assessed by vibration-controlled transient elastography (VCTE), correlates with hepatic fibrosis, an important predictor of liver-related and all-cause mortality. Although liver fat is associated with cardiovascular risk factors, the association between hepatic fibrosis and cardiovascular risk factors is less clear...

The purpose of this study by H. Fennoun et al. (University Hospital, Casablanca, Morocco) was to determine the interest of hepatic steatosis index in the detection of hepatic steatosis in patients with type 2 diabetes in order to establish an appropriate screening program of this disease in the population of diabetics hospitalized in Morocco...

Artificial intelligence uses computational methods that enable machines to learn from patterns and relationships in data in order to make predictions. Natural language processing can be used to extract knowledge from text, data can be modelled for the prediction of outcomes, and machine vision can analyse and recognise images...

Human mesenchymal stromal cells are adult stem cells, which feature hepatotropism. They support liver regeneration through amelioration of hepatic inflammation and lipid accumulation in a mouse model of NASH. To study mesenchymal stromal cells actions on fatty liver mechanistically, MJ Hsu et al...