Physical activity and NAFLD have an inverse association. However, studies assessing the impact of the widely accepted Physical Activity Guidelines for Americans on NAFLD are lacking.
D. Kim et al. (Stanford University School of Medicine, Stanford, USA) performed a serial, cross-sectional analysis among adults by using the 2007-2016 United States National Health and Nutrition Examination Survey. Of the 24,588 individuals, leisure-time physical activity (≥150 minutes/week) demonstrated 40% lower odds of NAFLD, whereas transportation-related physical activity was associated with 33% risk reduction in NAFLD.
Analysis of total physical activity and sitting times simultaneously showed a dose-response association between sitting time and NAFLD. Sedentary behavior appears as an independent predictor of NAFLD.