Commentary
A growing amount of evidence has correlated obstructive sleep apnea (OSA) with the presence of NAFLD and it has been demonstrated a direct association between the severity of the former and the progression of the latter. Thus, OSA patients should be screened for the presence and severity of NAFLD
Compared with controls, patients with biopsy proven NAFLD had significantly increased cancer incidence, due primarily to HCC, whereas the contribution of extrahepatic cancers was modest. Although HCC risk was highest with cirrhosis, substantial excess risk was also found with noncirrhotic fibrosis and comorbid diabetes.
