PPAR’S AS CRITICAL REGULATORS OF METABOLISM

The slide above illustrates the role of PPARα, PPARβ/δ and PPARγ as key regulators of lipid metabolism, inflammation and glucose metabolism. Understanding the role of various peroxisome proliferator-activated receptors and their ligands in clinical practice is very important for the future of NASH management. It illustrates why a “pan” PPAR approach can be beneficial and why more research is needed.

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