NAFLD and MAFLD as emerging causes of hepatocellular carcinoma

Commentary

Hepatocellular carcinoma is the most common type of liver cancer, increasingly arising in patients with NAFLD or MAFLD. S. Myers et al. (University of Geneva, Switzerland) assessed all patients with hepatocellular carcinoma between 1990 and 2014 in the canton of Geneva and found an increase in all hepatocellular carcinoma cases, particularly in women. They also found that hepatocellular carcinoma caused by NAFLD or MAFLD significantly increased over the years, particularly in women, possibly driving the increase in overall hepatocellular carcinoma cases.