Nowadays, the cornerstone in the clinical management of NAFLD includes two easy and pivotal concepts that are: dietary modification associated with improvement of physical activity.
In the era of evidence-based medicine, for L. Abenavoli et al. (Department of Health Sciences, University “Magna Graecia”, Catanzaro, Italy), Mediterranean diet can be considered the gold standard in preventive medicine targeting a vast spectrum of disorders involving the imbalance of the oxidative metabolism. On the basis of the data currently available in the literature, the authors suggest the prescription of Mediterranean diet in NAFLD patients, as an appropriate therapeutic approach, to prevent its onset and to contrast (or counteract?) the development of severe forms. Of course, longer-term trials testing the health benefits effects of Mediterranean diet remain warranted.