Children with suspected NAFLD: negative for other causes of liver disease

Commentary

T. Yodoshi et al. (Cincinnati Children’s Hospital Medical Center, USA) aimed to determine the prevalence of alternative causes of liver disease in a multicenter, retrospective cohort of 900 children with overweight and obesity patients aged ≤18 years with overweight and obesity, referred for suspected NAFLD.

In this large, multicentre cohort, the vast majority of children with overweight and obesity with presumed or confirmed NAFLD tested negative for other causes of liver disease. No patient was diagnosed with autoimmune hepatitis.