PanPPAR

PanPPAR is a computational tool for predicting the potential agonists or antagonists of Peroxisome Proliferator-Activated Receptors (PPARs), a class of nuclear receptors that play important roles in lipid and glucose metabolism, inflammation, and cellular differentiation. PanPPAR uses a combination of molecular docking and machine learning techniques to predict the binding affinity of small molecules to PPARs, which can be used to identify potential therapeutic agents or environmental toxins.

Emerging drugs targeting specific points in NASH pathogenesis

Authors: Stojsavljevic-Shapeski S, Duvnjak M, Virovic-Jukic L,
et al.
Published in J Clin Transl Hepatol 2021
Extensive research and revelation in the field of pathogenesis of NASH has offered new possibilities of treatment and emerging new drugs that are being tested currently in numerous preclinical and clinical trials. These drugs target almost all steps in the pathogenesis of NASH...
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