Physical Activity, Measured Objectively, is Associated With Lower Mortality in Patients With Nonalcoholic Fatty Liver Disease

D. Kim et al. (Stanford University School of Medicine, Stanford, California, United States) studied whether physical activity, measured by accelerometer, is associated with all-cause and cardiovascular mortality among individuals with NAFLD.
PUBLISHED IN: Clin Gastroenterol Hepatol 2020

The authors performed a longitudinal analysis using the 2003-2006 US National…

Commentary

D. Kim et al. (Stanford University School of Medicine, Stanford, California, United States) studied whether physical activity, measured by accelerometer, is associated with all-cause and cardiovascular mortality among individuals with NAFLD.

The authors performed a longitudinal analysis using the 2003-2006 US National Health and Nutrition Examination Survey data of adults and collecting mortality data through December 2015. NAFLD was defined based on hepatic steatosis index or US fatty liver index scores, in the absence of other causes of chronic liver disease. Physical activity was measured from participants who wore accelerometers 10 hrs/day for a minimum of 4 days over a 7-day period and classified as total physical activity, moderate to vigorous physical activity, and sedentary behaviour.

Total physical activity was associated with reduced risk of death, from any cause, in an age- and sex-adjusted model among individuals with NAFLD. Increasing duration of moderate to vigorous physical activity was associated with a lower risk of death from any cause in individuals with NAFLD. Furthermore, longer total physical activity was associated with a lower risk for cardiovascular disease-related death in individuals with NAFLD.

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Dr. D. Beard

DR. D. BEARD is specialist of Nash Pathology

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