New targets for NAFLD
In this review, the authors provide an update on the known molecular pathways involved in the pathophysiology of NAFLD and on ongoing studies of new therapeutic targets
Read More
Chronic vitamin C deficiency decreases NAFLD progression
This animal study aimed to reveal the role of vitamin C in NAFLD progression
Read More
NASH Epidemic: a call to action
NAFLD and NASH are common conditions with a rising burden. As pointed out by F. Kanwal et al. (Baylor College of Medicine, and Michael E. DeBakey Veterans Affairs Medical Center, Houston,
USA), “yet there are significant management gaps between clinical guidelines and practice in patients with NAFLD and NASH. Further, there is no single global guiding strategy for the management of
NAFLD and NASH.”
The American Gastroenterological Association, in collaboration with 7 professional associations, convened an international conference comprising 32 experts from the United States, Europe, Asia,
and Australia. The participants reviewed and discussed published literature on global burden, screening, risk stratification, diagnosis, and management of individuals with NAFLD and NASH.
Phytomedicines in experimental models of NAFLD
This systematic review aims to investigate the potential multi-targeting effects of plant-derived extracts in experimental models of NAFLD.
Read More
Liver organoid cultures and development of new therapeutic agents
In this review in Japanese, the authors outline the current issues in the diagnosis and treatment of NASH and introduce their research for the discovery of early diagnostic markers and the development of new therapeutic agents using liver organoid cultures derived from mouse models of NASH.
Read More
Physical activity, cardiorespiratory fitness and NAFLD
The authors investigated whether different physical activity intensities, and cardiorespiratory fitness, were independent predictors of non-alcoholic fatty liver disease.
Read More
Meta-analysis: NAFLD and melatonin supplementation
This meta-analysis was conducted to evaluate the effect of melatonin on liver indices in patients with NAFLD.
Read More
Emerging drugs targeting specific points in NASH pathogenesis
Extensive research and revelation in the field of pathogenesis of NASH has offered new possibilities of treatment and emerging new drugs that are being tested currently in numerous preclinical and clinical trials.
Read More
The Significance of the Mediterranean Diet in the Management of Non-Alcoholic Fatty Liver Disease: A Systematic Review
In this systematic review, the authors reviewed the effectiveness of the Mediterranean diet on NAFLD and its efficacy in disease management.
Read More
Eight recommendations to improve NAFLD care models
The authors developed a set of 8 recommendations to improve NAFLD care models and patient outcomes.
Read More