Outcomes in adults with NAFLD
In a new prospective study from the NASH Clinical Research Network, the authors describe outcomes for 1773 adults with biopsy-proven NAFLD with an average follow-up period of 4 years.
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Obese NAFLD children and adolescents: high BMI predicts liver fibrosis
This study aimed to investigate the predictors for liver fibrosis and the effects of short-term nutritional intervention on steatosis and fibrosis among obese..
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NAFLD in the elderly
In this review, the authors provide an overview of considerations relevant to the management and diagnosis of NAFLD in older adults.
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Diabetic kidney disease, cardiovascular disease and NAFLD
The aim of this review is “to raise awareness about the relationship of NAFLD, CVD and CKD in T2D patients and to improve our understanding and assessment of those conditions”.
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Asia, Middle East, North Africa: burden of NAFLD
Using Global Burden of Disease data, the authors aimed to assess the incidence, mortality, and disability-adjusted life years attributable to NAFLD-related liver complications in Asia, the Middle East and North Africa.
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NAFLD/NASH: clinical, economical, and patient related burdens
In this review, the authors focus on NAFLD/NASH and its clinical, economical, and patient related burdens.
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NASH Epidemic: a call to action
NAFLD and NASH are common conditions with a rising burden. As pointed out by F. Kanwal et al. (Baylor College of Medicine, and Michael E. DeBakey Veterans Affairs Medical Center, Houston,
USA), “yet there are significant management gaps between clinical guidelines and practice in patients with NAFLD and NASH. Further, there is no single global guiding strategy for the management of
NAFLD and NASH.”
The American Gastroenterological Association, in collaboration with 7 professional associations, convened an international conference comprising 32 experts from the United States, Europe, Asia,
and Australia. The participants reviewed and discussed published literature on global burden, screening, risk stratification, diagnosis, and management of individuals with NAFLD and NASH.
NAFLD unawareness in US adults
S. A. Alqahtani et al. (King Faisal Specialist Hospital and Research Centre, Saudi Arabia; Johns Hopkins University, USA) aimed to understand public awareness of NAFLD and its temporal trends.
They included 11,700 adults from five National Health and Nutrition Examination Surveys (2007-2016).
From 2007-2008 to 2015-2016, awareness of liver disease among adults with NAFLD improved from 4.4% to 6.3%, but 4 to 10 times lower than awareness about viral hepatitis. In 2015-2016, among
adults with NAFLD, awareness of liver disease was low among young adults and among non-Hispanic Blacks.
Nearly 96% of adults with NAFLD in the USA were unaware they had liver disease, especially among young adults and non-Hispanic Blacks.
Genetic and epigenetic factors determining NAFLD risk
This overview provides an insight into the genetic and epigenetic landscape of NAFLD.
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Review: MAFLF prevalence in children and adolescents
This review assesses the revised terminology and discusses the epidemiology, risk factors, pathophysiology, diagnosis, and prevention of MAFLD in children and adolescents worldwide and in Mexico, and the considers implications for public health.
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