New this week
The course of liver histology and morbi-mortality in NAFLD / NASH
Read MoreLiver organoid cultures and development of new therapeutic agents
Review: MAFLF prevalence in children and adolescents
Liver organoid cultures and development of new therapeutic agents
In this review in Japanese, the authors outline the current issues in the diagnosis and treatment of NASH and introduce their research for the discovery of early diagnostic markers and the development of new therapeutic agents using liver organoid cultures derived from mouse models of NASH.
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Review: MAFLF prevalence in children and adolescents
This review assesses the revised terminology and discusses the epidemiology, risk factors, pathophysiology, diagnosis, and prevention of MAFLD in children and adolescents worldwide and in Mexico, and the considers implications for public health.
Read MoreNASH and exposure to cigarette smoking
Current state and future possibilities in liver transplantation
NASH and exposure to cigarette smoking
The present study investigated the mechanisms of high fat diet and cigarette smoking, individually and in combination, on the pathogenesis of NASH in mice.
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Current state and future possibilities in liver transplantation
In this article, the authors point that liver cirrhosis due to NASH, alcoholic liver disease and hepatocellular carcinoma in cirrhosis are now among the leading indications for liver transplantation.
Read MoreThe course of liver histology and morbi-mortality in NAFLD / NASH
Prof. Manuel Romero-Gomez discusses the course of liver histology and its impact on mortality and morbidity in patients with NAFLD and NASH. He clarifies how fibrosis determines the prognosis of NAFLD and is the main therapeutic target. The importance of steatosis is also discussed both at the early phase and advanced phase. Finally he reviews the association with HCC and CV risks.
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