PPAR gamma agonists : what you need to know
Prof Sacks, USA reviews the available data about PPAR gamma agonist (Pioglitazone) especially data from the PROACTIVE study published in the Lancet in 2005
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Determining the reliability of liver biopsies in NASH clinical studies
The topic of liver biopsy in clinical studies, such as for treatments for NASH, is highly important.
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The effect of coffee consumption on the non-alcoholic fatty liver disease and liver fibrosis: a meta-analysis of eleven epidemiological studies
Coffee consumption may have a protective impact on NAFLD and liver fibrosis. However, the evidence from the previous studies is inconsistent
Read MoreDetermining the reliability of liver biopsies in NASH clinical studies
The effect of coffee consumption on the non-alcoholic fatty liver disease and liver fibrosis: a meta-analysis of eleven epidemiological studies
NAFLD and states of insulin resistance
Insulin resistance is tightly linked to NAFLD, particularly in those with Type 2 Diabetes.
In this video, Prof. Michael Roden, Germany discusses this link, its origins that can inherited or acquired. He also sheds light on the consequences of insulin resistance.
Fructose stimulated de novo lipogenesis is promoted by inflammation
Excessive fructose intake causes dysbiosis and tight-junction proteins downregulation, resulting in intestinal-barrier deterioration and low-grade endotoxaemia.
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Obstructive sleep apnea and severity of NAFLD
Obstructive sleep apnea (OSA) is associated with the development and evolution of NAFLD, independent of obesity or other shared risk factors.
Read MoreNAFLD and states of insulin resistance
Insulin resistance is tightly linked to NAFLD, particularly in those with Type 2 Diabetes.
In this video, Prof. Michael Roden, Germany discusses this link, its origins that can inherited or acquired. He also sheds light on the consequences of insulin resistance.